ESPE Abstracts

Background: Pituitary Stalk Interruption Syndrome (PSIS) is a rare congenital abnormality of the pituitary that is responsible for anterior pituitary deficiency. It is characterized by a classic triad of interrupted pituitary stalk, absent or ectopic posterior pituitary, and anterior pituitary hypoplasia or aplasia. Hypothalamic hypothyroidism, hyperprolactinemia and deficiency of anterior pituitary hormones are typical characteristics. Clinical presentation varies according t...